Publications

Choi T, Lacko LA, de Silva N, Liang NKham Hsi, Liu Y, Jamies EA, Evans T, Hurtado R.  2026.  3D imaging with enhanced transparency, signal-to-background ratios, and antigen detection using HyPer-3D.. Cell Rep Methods. 6(4):101375.

Tsao K-C, Bakis I, Sun S, Nakayama M, Kalmanson Z, Elmagid LAbd, Shuster JS, Xia Y, Eichenbaum JV, Yu FZhou et al..  2026.  Hypoxia-mediated epicardial signaling coordinates coronary angiogenesis and myocardial expansion during zebrafish ventricle maturation.. Proc Natl Acad Sci U S A. 123(26):e2536457123.

Liu Y, Choi T, Pearson B, Nachman R, Woo W, Xu N, Schreiner R, Hurtado R, Seandel M, Rafii S et al..  2026.  Restoration of spermatogenesis is dependent on activation of a SPRY4-ERK checkpoint following germline stem cell damage†.. Biol Reprod. 115(1):280-297.

Hanif SZ, Kutz C, Au CMCherie, Torregroza I, Palikhe S, Jannath SY, Fabiha T, Bhinder B, Washburn MP, Devost D et al..  2026.  Role of orphan G protein-coupled receptor GPR52 in breast cancer cell multicellular organization and collective invasion.. Br J Cancer.

Zhu J, Li Z, Xue D, Meng Z, Shao S, Pulecio J, Zhang G, Huangfu D, Evans T, Chen S et al..  2025.  A chemical epigenetic tool to probe site-specific DNA-binding protein complexes.. Proc Natl Acad Sci U S A. 122(40):e2509021122.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al..  2025.  ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

Ee L-S, Medina-Cano D, Goetzler E, Uyehara C, Schwarz C, Salataj E, Madhuranath S, Evans T, Hadjantonakis A-K, Apostolou E et al..  2025.  Enhancer remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm.. Dev Cell. 60(24):3431-3445.e8.

Bisson JA, Gordillo M, Kumar R, de Silva N, Yang E, Banks KM, Shi Z-D, Lee K, Yang D, Chung WK et al..  2025.  GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis.. Elife. 13

Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z et al..  2025.  A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection.. Adv Sci (Weinh). 12(36):e03932.

Zhang F, Evans T.  2025.  Stage-specific DNA methylation dynamics in mammalian heart development.. Epigenomics. 17(5):359-371.

Sam J, Torregroza I, Evans T.  2024.  Gata6 functions in zebrafish endoderm to regulate late differentiating arterial pole cardiogenesis.. Development. 151(17)

Yang L, Han Y, Zhang T, Dong X, Ge J, Roy A, Zhu J, Lu T, J Vandana J, de Silva N et al..  2024.  Human vascularized macrophage-islet organoids to model immune-mediated pancreatic β cell pyroptosis upon viral infection.. Cell Stem Cell. 31(11):1612-1629.e8.

Duan X, Zhang T, Feng L, de Silva N, Greenspun B, Wang X, Moyer J, M Martin L, Chandwani R, Elemento O et al..  2024.  A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS.. Cell Stem Cell. 31(1):71-88.e8.

Yang L, Kim TWan, Han Y, Nair MS, Harschnitz O, Zhu J, Wang P, Koo SYeon, Lacko LA, Chandar V et al..  2024.  SARS-CoV-2 infection causes dopaminergic neuron senescence.. Cell Stem Cell. 31(2):196-211.e6.

Das BC, Yadav P, Das S, Saito M, Evans T.  2023.  Development of a New Methodology for Dearomative Borylation of Coumarins and Chromenes and Its Applications to Synthesize Boron-Containing Retinoids.. Molecules. 28(3)

Zhong L, Gordillo M, Wang X, Qin Y, Huang Y, Soshnev A, Kumar R, Nanjangud G, James D, C Allis D et al..  2023.  Dual role of lipids for genome stability and pluripotency facilitates full potency of mouse embryonic stem cells.. Protein Cell. 14(8):591-602.

Yang L, Arbona RJRicart, Smith CS, Banks KM, V Thomas K, Palmer L, Evans T, Hurtado R.  2023.  An evolutionarily conserved pacemaker role for HCN ion channels in smooth muscle.. J Physiol. 601(7):1225-1246.

Lee D, Le Pen J, Yatim A, Dong B, Aquino Y, Ogishi M, Pescarmona R, Talouarn E, Rinchai D, Zhang P et al..  2023.  Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.. Science. 379(6632):eabo3627.

Yang L, Han Y, Zhou T, Lacko LA, Saeed M, Tan C, Danziger R, Zhu J, Zhao Z, Cahir C et al..  2023.  Isogenic human trophectoderm cells demonstrate the role of NDUFA4 and associated variants in ZIKV infection.. iScience. 26(7):107001.

Tang X, Xue D, Zhang T, Nilsson-Payant BE, Carrau L, Duan X, Gordillo M, Tan AY, Qiu Y, Xiang J et al..  2023.  A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infection.. Nat Cell Biol. 25(3):381-389.

Sleiman Y, Reiken S, Charrabi A, Jaffré F, Sittenfeld LR, Pasquié J-L, Colombani S, Lerman BB, Chen S, Marks AR et al..  2023.  Personalized medicine in the dish to prevent calcium leak associated with short-coupled polymorphic ventricular tachycardia in patient-derived cardiomyocytes.. Stem Cell Res Ther. 14(1):266.

Luo Y, Yamada M, N'Tumba-Byn T, Asif H, Gao M, Hu Y, Marangoni P, Liu Y, Evans T, Rafii S et al..  2023.  SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline†.. Biol Reprod. 109(4):533-551.

Tan L, Duan X, Mutyala P, Zhou T, Amin S, Zhang T, Herbst B, Askan G, Itkin T, Xiang Z et al..  2023.  A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells.. J Mol Cell Biol. 15(6)

Das BC, Nandwana NK, Das S, Nandwana V, Shareef MAdil, Das Y, Saito M, Weiss LM, Almaguel F, Hosmane NS et al..  2022.  Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective.. Molecules. 27(9)

Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai S-Y, Khalaj M, Zhou T, Samuel RM et al..  2022.  A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.. iScience. 25(4):104153.